La determine 1 représente un schéma du cycle de Krebs et le rôle de l’aconitase mitochondriale dans le cycle de Krebs. La peau qui vieillit perd son élasticité et devient relâchée. Elle s'affine et se déshydrate. Les vaisseaux capillaires du derme se dilatent, donnant des taches rouges et de la couperose. Les rides se marquent là où se
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